Sandbox Reserved 1095: Difference between revisions
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=== Interaction with drugs === | === Interaction with drugs === | ||
====Olmesartan, candesartan, telmisartan, and valsartan==== | ====Olmesartan, candesartan, telmisartan, and valsartan==== | ||
Olmesartan anchored to ATR1 by the residues Tyr35, Trp84 and Arg167. | Olmesartan anchored to ATR1 by the residues Tyr35, Trp84<scene name='82/829348/Trp84/2'>Text To Be Displayed</scene> and Arg167. | ||
Those amino acids seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref> http://www.jbc.org/content/290/49/29127 </ref>. | Those amino acids seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref> http://www.jbc.org/content/290/49/29127 </ref>. | ||
