Sandbox Reserved 1092: Difference between revisions

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Myostatin <ref name="edumont">Université de Montpellier. Physiologie et médecien fondamentale du coeur et des muscles : myostatine. [https://u1046.edu.umontpellier.fr/163-2/abrege-des-proteines-musculaires/myostatine/]</ref> is a protein that has a control over muscle development: it is a negative regulator of squeletics muscles. It has a very important role during the development of the animals but also during its whole life. It is a very important protein that is very conserved from zebra fish to humans <ref name="patho">PMID:19412331</ref> and so it has to be very well regulated. Indeed, there are many ways that regulates the action of this protein and at many scales.

It is a grown factor<ref name="patho"/> that is implicated into muscle development in mammals. Myostatin can transmit a message to the nucleus that will promote a gene that lead to the production of ubiquitin. Ubiquitin is a signal of degradation so muscle cells will be destroyed. Indeed, it reduce the mass of the muscle but it also reduces the quantity of {{~~http~~:~~//proteopedia.org/wiki/index.php/~~Myosin}} <ref>Jeffrey L. Corden,David Tollervey. Cell Biology, Chapter 36 Motor Proteins.2017 [https://doi.org/10.1016/B978-0-323-34126-4.00036-0 DOI:10.1016/B978-0-323-34126-4.00036-0] </ref> which is very important for the cohesion of muscles and for movement. Indeed myosin forms filament, and when myosin filaments associate with actin and consume ATP it produce muscle movement.

It is a grown factor<ref name="patho"/> that is implicated into muscle development in mammals. Myostatin can transmit a message to the nucleus that will promote a gene that lead to the production of ubiquitin. Ubiquitin is a signal of degradation so muscle cells will be destroyed. Indeed, it reduce the mass of the muscle but it also reduces the quantity of {{:Myosin}} <ref>Jeffrey L. Corden,David Tollervey. Cell Biology, Chapter 36 Motor Proteins.2017 [https://doi.org/10.1016/B978-0-323-34126-4.00036-0 DOI:10.1016/B978-0-323-34126-4.00036-0] </ref> which is very important for the cohesion of muscles and for movement. Indeed myosin forms filament, and when myosin filaments associate with actin and consume ATP it produce muscle movement.

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Revision as of 16:13, 11 January 2020 view source Morgane Mura (talk \| contribs) 38 edits No edit summary ← Older edit		Revision as of 16:15, 11 January 2020 view source Morgane Mura (talk \| contribs) 38 edits No edit summary Newer edit →
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	Myostatin <ref name="edumont">Université de Montpellier. Physiologie et médecien fondamentale du coeur et des muscles : myostatine. [https://u1046.edu.umontpellier.fr/163-2/abrege-des-proteines-musculaires/myostatine/]</ref> is a protein that has a control over muscle development: it is a negative regulator of squeletics muscles. It has a very important role during the development of the animals but also during its whole life. It is a very important protein that is very conserved from zebra fish to humans <ref name="patho">PMID:19412331</ref> and so it has to be very well regulated. Indeed, there are many ways that regulates the action of this protein and at many scales.		Myostatin <ref name="edumont">Université de Montpellier. Physiologie et médecien fondamentale du coeur et des muscles : myostatine. [https://u1046.edu.umontpellier.fr/163-2/abrege-des-proteines-musculaires/myostatine/]</ref> is a protein that has a control over muscle development: it is a negative regulator of squeletics muscles. It has a very important role during the development of the animals but also during its whole life. It is a very important protein that is very conserved from zebra fish to humans <ref name="patho">PMID:19412331</ref> and so it has to be very well regulated. Indeed, there are many ways that regulates the action of this protein and at many scales.

	It is a grown factor<ref name="patho"/> that is implicated into muscle development in mammals. Myostatin can transmit a message to the nucleus that will promote a gene that lead to the production of ubiquitin. Ubiquitin is a signal of degradation so muscle cells will be destroyed. Indeed, it reduce the mass of the muscle but it also reduces the quantity of {{~~http~~:~~//proteopedia.org/wiki/index.php/~~Myosin}} <ref>Jeffrey L. Corden,David Tollervey. Cell Biology, Chapter 36 Motor Proteins.2017 [https://doi.org/10.1016/B978-0-323-34126-4.00036-0 DOI:10.1016/B978-0-323-34126-4.00036-0] </ref> which is very important for the cohesion of muscles and for movement. Indeed myosin forms filament, and when myosin filaments associate with actin and consume ATP it produce muscle movement.		It is a grown factor<ref name="patho"/> that is implicated into muscle development in mammals. Myostatin can transmit a message to the nucleus that will promote a gene that lead to the production of ubiquitin. Ubiquitin is a signal of degradation so muscle cells will be destroyed. Indeed, it reduce the mass of the muscle but it also reduces the quantity of {{:Myosin}} <ref>Jeffrey L. Corden,David Tollervey. Cell Biology, Chapter 36 Motor Proteins.2017 [https://doi.org/10.1016/B978-0-323-34126-4.00036-0 DOI:10.1016/B978-0-323-34126-4.00036-0] </ref> which is very important for the cohesion of muscles and for movement. Indeed myosin forms filament, and when myosin filaments associate with actin and consume ATP it produce muscle movement.