Sandbox Reserved 1104: Difference between revisions
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Introduction == | == Introduction == | ||
Bilirubin oxidase is an enzyme known to catalyze the oxidation of bilirubin to biliverdin by reducting O2 in water. It’s a multicopper oxidase which can exist under two different structures in the ascomycete Myrothecium verrucaria (see the 3abg one insert link http://proteopedia.org/wiki/index.php/3abg). The 2xII form is a 4 chain structure with 8 ligands NAG-NAG belonging to the family of oxidoreductases. | |||
It was first isolated in 1981 by the scientists Sawao Murao and Noriaki Tanaka as they tried to find a microorganism able to decolore raw sewage and to use it as an analytical tool in clinical fields. Now, bilirubin oxidase may be used to determine free hemoglobin in icteric specimens and can be use as a treatment for neonatal jaundice. | |||
Moreover, the bilirubin oxidase is an enzyme that is active in porphyrin and chlorophyll metabolism. | |||
== Structure == | == Structure == | ||
