Sandbox Reserved 1091: Difference between revisions
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The mechanism is the following: The histidine will react with the Serine and deprotonate it. The deprotonated hydroxyl group of the serine will act as a nucleophilic species and attack the carbon from the carbonyl function on the peptide. This will lead to the formation of a tetrahedral intermediate. At the end, the regeneration of the active site will be done with the release of the peptide cut in two parts. | The mechanism is the following: The histidine will react with the Serine and deprotonate it. The deprotonated hydroxyl group of the serine will act as a nucleophilic species and attack the carbon from the carbonyl function on the peptide. This will lead to the formation of a tetrahedral intermediate. At the end, the regeneration of the active site will be done with the release of the peptide cut in two parts. | ||
== Disease == | == Disease == | ||
