Sandbox TYRP1: Difference between revisions
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The cystein-rich domain and the tyrosinase-like subdomain | The cystein-rich domain and the tyrosinase-like subdomain stongly interact together by the last loop of the cystein-rich domain preceding the N-terminal domain. The role of the cystein-rich domain is still unknown, it is only found in mammalians but 3D-structure highlights two pairs of short antiparallel beta-strands which create loops. This domain is stabilize by five disulfide bounds and is located at the opposite of the active site.<ref name="lai"/> | ||
=== The active site === | === The active site === | ||
The active site is delimited by four helice and contain the binuclearmetal binding site. | The active site is delimited by four helice and contain the binuclearmetal binding site. | ||