Sandbox Reserved 1091: Difference between revisions
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Moreover, we can find three <scene name='82/829344/Calcium_binding_sites/2'>Ca2+ Binding Sites</scene> in the ASP Structure (Ca1, Ca2 and Ca3). <scene name='82/829344/Ca1_et_ca2/4'>Ca1 and Ca2</scene> are situated in the N-terminal domain, and <scene name='82/829344/Ca3/3'>Ca3</scene> is situated in the C-terminal domain. It were assigned to ASP based on electron density, counter charges, and coordination. But in contrary to Kex2 ([[1r64]]), ASP contains no Ca2+ binding sites near its catalytic site. | Moreover, we can find three <scene name='82/829344/Calcium_binding_sites/2'>Ca2+ Binding Sites</scene> in the ASP Structure (Ca1, Ca2 and Ca3). <scene name='82/829344/Ca1_et_ca2/4'>Ca1 and Ca2</scene> are situated in the N-terminal domain, and <scene name='82/829344/Ca3/3'>Ca3</scene> is situated in the C-terminal domain. It were assigned to ASP based on electron density, counter charges, and coordination. But in contrary to Kex2 ([[1r64]]), ASP contains no Ca2+ binding sites near its catalytic site. | ||
A schematic representation of the domains of the protein can be observed : [https://www.degruyter.com/viewimg/j/bchm.2017.398.issue-10/hsz-2016-0344/hsz-2016-0344.xml?img=graphic/j_hsz-2016-0344_fig_001.jpg '''secondary structure of ASP'''] | |||
We can see that Kex2 has the propeptide (in yellow) that is absent in ASP. The occluding subdomains in the C-terminal region of ASP are shown in dark blue. | |||
