Sandbox Reserved 1097: Difference between revisions
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* '''The cystein-rich subdomain''' ''(25-126)'' | * '''The cystein-rich subdomain''' ''(25-126)'' | ||
The <scene name='82/829350/Domains/1'>cystein-rich domain</scene> has an epidermal growth factor‐like fold formed by <scene name='82/829350/Beta-strands_cys-rich_domain/1'>two pairs of short antiparallel β-strands</scene> (62-66/98-102 and 116-118/124-126)<ref name= "lai"/> . This previous domain strongly interacts with the tyrosinase-like subdomain by the lastloop of the cystein-rich domain preceding the N-terminal domain. The role of the cystein-rich domain is still unknown, it is only found in [https://en.wikipedia.org/wiki/Mammal mammalians] | The <scene name='82/829350/Domains/1'>cystein-rich domain</scene> has an epidermal growth factor‐like fold formed by <scene name='82/829350/Beta-strands_cys-rich_domain/1'>two pairs of short antiparallel β-strands</scene> (62-66/98-102 and 116-118/124-126)<ref name= "lai"/> . This previous domain strongly interacts with the tyrosinase-like subdomain by the lastloop of the cystein-rich domain preceding the N-terminal domain. This domain is stabilized by three (42-65/56-99/101-110) disulfide bounds and is located at the opposite of the active site. The role of the cystein-rich domain is still unknown, it is only found in [https://en.wikipedia.org/wiki/Mammal mammalians]. It is said that the cystein-rich domain might help the formation of a complex between TYR and TYRP2.<ref name="Xlai"/><ref name= "lai"/> | ||
* '''The tyrosinase-like subdomain''' ''(127-477)'' | * '''The tyrosinase-like subdomain''' ''(127-477)'' | ||
