Sandbox Reserved 1100: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 26: Line 26:




Obesity and insulin resistance also lead to [http://en.wikipedia.org/wiki/Metabolic_syndrome metabolic syndrome]. But agonist of adiponectin receptor (AdipoR1) should be a new treatment strategie for metabolic syndrome or obesity-linked diseases. <ref name="doc3"/>
Obesity and insulin resistance also lead to [http://en.wikipedia.org/wiki/Metabolic_syndrome metabolic syndrome].Indeed,adipoR1 can display metabolic dysfunction, especially in case of the drop of its expression<ref name="doc5"/>.However agonist of adiponectin receptor (AdipoR1) should be a new treatment strategie for metabolic syndrome or obesity-linked diseases<ref name="doc3"/>.Moreover,a treatment against type II diabete and insulin resistance could be AdipoR1 overexpression, which improves insulin resistance and promotes glucose uptake in skeletal muscle in one hand, and attenuates weight gain and improves glucose metabolism models of metabolic dysfunction in macrophages in the other hand<ref name="doc5"/>.
AdipoR1 can display metabolic dysfunction, especially in case of the drop of its expression. <ref name="doc5"/>
A treatment against type II diabete and insulin resistance could be AdipoR1 overexpression that improves insulin resistance and promotes glucose uptake in skeletal muscle in one hand, and attenuates weight gain and improves glucose metabolism models of metabolic dysfunction in macrophages.  <ref name="doc5"/>