6qgo: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6qgo is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of APT1 S119A mutant bound to palmitic acid.==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6qgo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGO OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGO FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6qgn|6qgn]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgo OCA], [http://pdbe.org/6qgo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgo RCSB], [http://www.ebi.ac.uk/pdbsum/6qgo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgo ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/LYPA1_HUMAN LYPA1_HUMAN]] Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity.<ref>PMID:20418879</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Audagnotto, M]]

[[Category: Goot, G Van der]]

[[Category: Ho, S]]

[[Category: Marcaida, M J]]

[[Category: Peraro, M Dal]]

[[Category: Pojer, F]]

[[Category: Acyl-protein thioesterase]]

[[Category: Depalmitoylation]]

[[Category: Hydrolase]]

[[Category: Palmitic acid]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6qgo is ON HOLD  until Paper Publication
+==Crystal structure of APT1 S119A mutant bound to palmitic acid.==
+<StructureSection load='6qgo' size='340' side='right'caption='[[6qgo]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6qgo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGO FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qgn|6qgn]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgo OCA], [http://pdbe.org/6qgo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgo RCSB], [http://www.ebi.ac.uk/pdbsum/6qgo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgo ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/LYPA1_HUMAN LYPA1_HUMAN]] Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity.<ref>PMID:20418879</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Audagnotto, M]]
+[[Category: Goot, G Van der]]
+[[Category: Ho, S]]
+[[Category: Marcaida, M J]]
+[[Category: Peraro, M Dal]]
+[[Category: Pojer, F]]
+[[Category: Acyl-protein thioesterase]]
+[[Category: Depalmitoylation]]
+[[Category: Hydrolase]]
+[[Category: Palmitic acid]]