6vi7: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6vi7 is ~~ON HOLD until Paper Publication~~

==Probing extradiol dioxygenase mechanism in NAD(+) biosynthesis by viewing reaction cycle intermediates - a substrate bidentately bound structure==

~~Authors~~: ~~Wang~~, Y., ~~Liu~~, F., ~~Yang~~, Y., ~~Liu, A~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[6vi7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VI7 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VI7 FirstGlance].

~~Description: Probing Extradiol Dioxygenase Mechanism in NAD+ Biosynthesis by Viewing Reaction Cycle Intermediates-a substrate bidentately bound structure~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=3HA:3-HYDROXYANTHRANILIC+ACID'>3HA</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/3-hydroxyanthranilate_3,4-dioxygenase 3-hydroxyanthranilate 3,4-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.6 1.13.11.6] </td></tr>

[[Category: ~~Yang~~, Y]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vi7 OCA], [http://pdbe.org/6vi7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vi7 RCSB], [http://www.ebi.ac.uk/pdbsum/6vi7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vi7 ProSAT]</td></tr>

[[Category: ~~Wang, Y~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/3HAO_CUPMC 3HAO_CUPMC]] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[HAMAP-Rule:MF_00825]<ref>PMID:15909977</ref>

== References ==

__TOC__

</StructureSection>

[[Category: 3-hydroxyanthranilate 3,4-dioxygenase]]

[[Category: Large Structures]]

[[Category: Liu, A]]

[[Category: Liu, F]]

[[Category: Wang, Y]]

[[Category: Yang, Y]]

[[Category: Extradiol dioxygenase]]

[[Category: In crystallo reaction]]

[[Category: Intermediate]]

[[Category: Nad+ biosynthesis]]

[[Category: Oxidoreductase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6vi7 is ON HOLD  until Paper Publication
+==Probing extradiol dioxygenase mechanism in NAD(+) biosynthesis by viewing reaction cycle intermediates - a substrate bidentately bound structure==
+<StructureSection load='6vi7' size='340' side='right'caption='[[6vi7]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
-Authors: Wang, Y., Liu, F., Yang, Y., Liu, A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6vi7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VI7 FirstGlance]. <br>
-Description: Probing Extradiol Dioxygenase Mechanism in NAD+ Biosynthesis by Viewing Reaction Cycle Intermediates-a substrate bidentately bound structure
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HA:3-HYDROXYANTHRANILIC+ACID'>3HA</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyanthranilate_3,4-dioxygenase 3-hydroxyanthranilate 3,4-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.6 1.13.11.6] </span></td></tr>
-[[Category: Yang, Y]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vi7 OCA], [http://pdbe.org/6vi7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vi7 RCSB], [http://www.ebi.ac.uk/pdbsum/6vi7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vi7 ProSAT]</span></td></tr>
-[[Category: Wang, Y]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/3HAO_CUPMC 3HAO_CUPMC]] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[HAMAP-Rule:MF_00825]<ref>PMID:15909977</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: 3-hydroxyanthranilate 3,4-dioxygenase]]
+[[Category: Large Structures]]
 [[Category: Liu, A]]
 [[Category: Liu, F]]
+[[Category: Wang, Y]]
+[[Category: Yang, Y]]
+[[Category: Extradiol dioxygenase]]
+[[Category: In crystallo reaction]]
+[[Category: Intermediate]]
+[[Category: Nad+ biosynthesis]]
+[[Category: Oxidoreductase]]