6t7y: Difference between revisions
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==Structure of PCNA bound to cPIP motif of DP2 from P. abyssi== | |||
<StructureSection load='6t7y' size='340' side='right'caption='[[6t7y]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6t7y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6T7Y FirstGlance]. <br> | |||
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6t7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t7y OCA], [http://pdbe.org/6t7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6t7y RCSB], [http://www.ebi.ac.uk/pdbsum/6t7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6t7y ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PCNA_PYRAB PCNA_PYRAB]] Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Regulates activity of NucS endonuclease and prevents non-specific cleavage.[HAMAP-Rule:MF_00317]<ref>PMID:22431731</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: DNA-directed DNA polymerase]] | |||
[[Category: Large Structures]] | |||
[[Category: Beaufet, I Hugonneau]] | |||
[[Category: Carroni, M]] | |||
[[Category: Delarue, M]] | |||
[[Category: Madru, C]] | |||
[[Category: Raia, P]] | |||
[[Category: Sauguet, L]] | |||
[[Category: Dp2]] | |||
[[Category: Pcna]] | |||
[[Category: Pip-box]] | |||
[[Category: Pold]] | |||
[[Category: Replication]] | |||
Revision as of 06:52, 4 March 2020
Structure of PCNA bound to cPIP motif of DP2 from P. abyssi
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