6ulw: Difference between revisions
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<StructureSection load='6ulw' size='340' side='right'caption='[[6ulw]], [[Resolution|resolution]] 3.40Å' scene=''> | <StructureSection load='6ulw' size='340' side='right'caption='[[6ulw]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6ulw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ULW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ULW FirstGlance]. <br> | <table><tr><td colspan='2'>[[6ulw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_stratosphericus_lama_585 Bacillus stratosphericus lama 585]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ULW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ULW FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C883_1060 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1236481 Bacillus stratosphericus LAMA 585])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ulw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ulw OCA], [http://pdbe.org/6ulw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ulw RCSB], [http://www.ebi.ac.uk/pdbsum/6ulw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ulw ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ulw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ulw OCA], [http://pdbe.org/6ulw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ulw RCSB], [http://www.ebi.ac.uk/pdbsum/6ulw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ulw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Nonribosomal depsipeptides are natural products composed of amino and hydroxy acid residues. The hydroxy acid residues often derive from alpha-keto acids, reduced by ketoreductase domains in the depsipeptide synthetases. Biochemistry and structures reveal the mechanism of discrimination for alpha-keto acids and a remarkable architecture: flanking intact adenylation and ketoreductase domains are sequences separated by >1,100 residues that form a split 'pseudoAsub' domain, structurally important for the depsipeptide module's synthetic cycle. | |||
Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis.,Alonzo DA, Chiche-Lapierre C, Tarry MJ, Wang J, Schmeing TM Nat Chem Biol. 2020 Feb 17. pii: 10.1038/s41589-020-0481-5. doi:, 10.1038/s41589-020-0481-5. PMID:32066969<ref>PMID:32066969</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 6ulw" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacillus stratosphericus lama 585]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Alonzo, D A]] | [[Category: Alonzo, D A]] | ||
