6vs4: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6vs4 is ON HOLD~~

==Crystal structure of ADP RIBOSYLATION FACTOR-LIKE GTP BINDING PROTEIN /Small COPII coat GTPase SAR1 from Encephalitozoon cuniculi in complex with GDP==

~~Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6vs4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VS4 FirstGlance]. <br>

~~Description:~~ Crystal structure of ADP RIBOSYLATION FACTOR-LIKE GTP BINDING PROTEIN /Small COPII coat GTPase SAR1 from Encephalitozoon cuniculi in complex with GDP

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vs4 OCA], [http://pdbe.org/6vs4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vs4 RCSB], [http://www.ebi.ac.uk/pdbsum/6vs4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vs4 ProSAT]</span></td></tr>

[[Category: ~~Seattle~~ Structural ~~Genomics Center For Infectious Disease (~~Ssgcid)]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/SAR1_ENCCU SAR1_ENCCU]] Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Structural genomic]]

[[Category: Adp ribosylation factor-like gtp binding protein]]

[[Category: Copii coat gtpase sar1]]

[[Category: Hydrolase]]

[[Category: Ssgcid]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6vs4 is ON HOLD
+==Crystal structure of ADP RIBOSYLATION FACTOR-LIKE GTP BINDING PROTEIN /Small COPII coat GTPase SAR1 from Encephalitozoon cuniculi in complex with GDP==
+<StructureSection load='6vs4' size='340' side='right'caption='[[6vs4]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6vs4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VS4 FirstGlance]. <br>
-Description: Crystal structure of ADP RIBOSYLATION FACTOR-LIKE GTP BINDING PROTEIN /Small COPII coat GTPase SAR1 from Encephalitozoon cuniculi in complex with GDP
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vs4 OCA], [http://pdbe.org/6vs4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vs4 RCSB], [http://www.ebi.ac.uk/pdbsum/6vs4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vs4 ProSAT]</span></td></tr>
-[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/SAR1_ENCCU SAR1_ENCCU]] Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Structural genomic]]
+[[Category: Adp ribosylation factor-like gtp binding protein]]
+[[Category: Copii coat gtpase sar1]]
+[[Category: Hydrolase]]
+[[Category: Ssgcid]]