Tryptophan synthase: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
The <scene name='52/525189/Cv/6'>active site</scene> of TrpS subunit α contains the catalytic residues Glu and Asp<ref>PMID:16120446</ref>. Water molecules are shown as red spheres. | The <scene name='52/525189/Cv/6'>active site</scene> of TrpS subunit α contains the catalytic residues Glu and Asp<ref>PMID:16120446</ref>. Water molecules are shown as red spheres. | ||
==3D structures of tryptophan synthase== | |||
[[Tryptophan synthase 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
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*'''Tryptophan synthase α subunit''' | *'''Tryptophan synthase α subunit''' | ||
**[[1rd5]] - TrpS α subunit – corn<br /> | |||
**[[3vnd]] - TrpS α subunit – ''Shewanella frigidimarina''<br /> | **[[3vnd]] - TrpS α subunit – ''Shewanella frigidimarina''<br /> | ||
**[[3tha]] - TrpS α subunit – ''Campylobacter jejuni''<br /> | **[[3tha]] - TrpS α subunit – ''Campylobacter jejuni''<br /> | ||
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**[[1geq]] - PfTrpS α subunit - ''Pyrococcus furiosus''<br /> | **[[1geq]] - PfTrpS α subunit - ''Pyrococcus furiosus''<br /> | ||
**[[2dzp]], [[2dzs]], [[2dzt]], [[2dzu]], [[2dzv]], [[2dzw]], [[2dzx]], [[2e09]] - PfTrpS α subunit (mutant)<br /> | **[[2dzp]], [[2dzs]], [[2dzt]], [[2dzu]], [[2dzv]], [[2dzw]], [[2dzx]], [[2e09]] - PfTrpS α subunit (mutant)<br /> | ||
**[[1ujp]] - TtTrpS α subunit <br /> | **[[1ujp]] - TtTrpS α subunit <br /> | ||
**[[1v7y]], [[1wq5]], [[1xc4]] - EcTrpS α subunit <br /> | **[[1v7y]], [[1wq5]], [[1xc4]] - EcTrpS α subunit <br /> | ||
**[[1xcf]] - EcTrpS α subunit (mutant)<br /> | **[[1xcf]] - EcTrpS α subunit (mutant)<br /> | ||
**[[2ekc]] - TrpS α subunit – ''Aquifex aeolicus''<br /> | **[[2ekc]] - TrpS α subunit – ''Aquifex aeolicus''<br /> | ||
**[[5kmy]], [[5k9x]] - TrpS α subunit – ''Legionella pneumophila''<br /> | **[[5kmy]], [[5k9x]], [[6oky]] - TrpS α subunit – ''Legionella pneumophila''<br /> | ||
**[[5n2p]] - SsTrpS α subunit – ''Sulfolobus solfataricus''<br /> | |||
*Tryptophan synthase α binary complex | *Tryptophan synthase α binary complex | ||
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**[[1v8z]] - PfTrpS β1 subunit <br /> | **[[1v8z]] - PfTrpS β1 subunit <br /> | ||
**[[4neg]] - TrpS β subunit – ''Bacillus anthracis''<br /> | **[[4neg]] - TrpS β subunit – ''Bacillus anthracis''<br /> | ||
**[[4qys]] - SsTrpS β2 subunit | **[[4qys]], [[6hte]] - SsTrpS β2 subunit<br /> | ||
*Tryptophan synthase β complex | *Tryptophan synthase β complex | ||
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**[[1wdw]] - PfTrpS α + β subunits <br /> | **[[1wdw]] - PfTrpS α + β subunits <br /> | ||
**[[6hul]] - SsTrpS α + β subunits <br /> | |||
*Tryptophan synthase α+β binary complex | *Tryptophan synthase α+β binary complex | ||
**[[1ttp]], [[1ttq]], [[1bks]], [[2wsy]], [[1kfk]] - StTrpS α + β + PLP – ''Salmonella typhimurium''<br /> | **[[1ttp]], [[1ttq]], [[1bks]], [[2wsy]], [[1kfk]] - StTrpS α + β + PLP – ''Salmonella typhimurium''<br /> | ||
**[[1k7x]], [[2j9z]] - StTrpS α + β (mutant) + PLP<br /> | |||
**[[3pr2]], [[4hn4]], [[4hpj]], [[4hpx]], [[4ht3]], [[4kkx]] - StTrpS α + β + inhibitor<br /> | |||
**[[1kfj]] - StTrpS α + β + pyridoxal-serine-monophsphate<br /> | |||
**[[1a5a]], [[1k8x]] - StTrpS α (mutant) + β + PLP<br /> | **[[1a5a]], [[1k8x]] - StTrpS α (mutant) + β + PLP<br /> | ||
**[[1kfe]] - StTrpS α (mutant) + β + pyridoxal-serine-monophsphate<br /> | **[[1kfe]] - StTrpS α (mutant) + β + pyridoxal-serine-monophsphate<br /> | ||
**[[ | **[[6o1h]], [[6dzo]], [[6duc]], [[6d0v]], [[6c73]] - StTrpS α + β (mutant) + inhibitor<br /> | ||
**[[2j9y]] - StTrpS α + β (mutant) + enoic acid derivative<br /> | **[[2j9y]] - StTrpS α + β (mutant) + enoic acid derivative<br /> | ||
**[[ | **[[2tys]] - StTrpS α (mutant) + β (mutant) + Trp derivative<br /> | ||
**[[5kzm]] - TrpS α + β + PLP derivative – ''Francisella tularensis''<br /> | **[[5kzm]] - TrpS α + β + PLP derivative – ''Francisella tularensis''<br /> | ||
**[[5kin]] - TrpS α + β + PLP derivative – ''Streptococcus pneumoniae''<br /> | **[[5kin]] - TrpS α + β + PLP derivative – ''Streptococcus pneumoniae''<br /> | ||
