6ql6: Difference between revisions
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==Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom== | |||
<StructureSection load='6ql6' size='340' side='right'caption='[[6ql6]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ql6]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QL6 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=J8T:[(3~{R})-4-azanyl-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl]+dihydrogen+phosphate'>J8T</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ql6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ql6 OCA], [http://pdbe.org/6ql6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ql6 RCSB], [http://www.ebi.ac.uk/pdbsum/6ql6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ql6 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/FAS2_YEAST FAS2_YEAST]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for: acyl carrier protein, 3-oxoacyl-[acyl-carrier-protein] reductase, and 3-oxoacyl-[acyl-carrier-protein] synthase. This subunit coordinates the binding of the six beta subunits to the enzyme complex.[HAMAP-Rule:MF_00101] [[http://www.uniprot.org/uniprot/FAS1_YEAST FAS1_YEAST]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Chari, A]] | |||
[[Category: Graf, B]] | |||
[[Category: Linden, A]] | |||
[[Category: Sautner, V]] | |||
[[Category: Singh, K]] | |||
[[Category: Stark, H]] | |||
[[Category: Tittmann, K]] | |||
[[Category: Urlaub, H]] | |||
[[Category: Acetyl transferase]] | |||
[[Category: Acyl carrier protein]] | |||
[[Category: Dehydratase]] | |||
[[Category: Enoyl reductase]] | |||
[[Category: Fatty acid synthase]] | |||
[[Category: Ketoreductase]] | |||
[[Category: Ketosynthase]] | |||
[[Category: Malonyl/palmitoyl transferase]] | |||
[[Category: Phosphopantetheine transferase]] | |||
[[Category: Transferase]] | |||
Revision as of 09:45, 18 March 2020
Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom
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