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| [[Urokinase 3D Structures]] | | [[Urokinase 3D Structures]] |
| </StructureSection> | | </StructureSection> |
| == 3D Structures of urokinase ==
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *Urokinase
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| **[[2i9a]] - hUK Hc N terminal (residues 21-163) - human<br />
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| **[[1urk]] - hUK Hc N terminal – NMR<br />
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| **[[1kdu]] – hUK kringle domain (residues 69-153) - NMR<br />
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| **[[4dva]] – hUK catalytic domain (residues 179-431) <br />
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| **[[4xsk]] - hUK catalytic domain (mutant) <br />
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| **[[5lhs]] - UK catalytic domain (mutant) - mouse<br />
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| *Urokinase catalytic domain 179-424 complex with inhibitors
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| **[[4fu7]], [[4fu8]], [[4fu9]], [[4fub]], [[5xg4]], [[5wxs]] - hUK + inhibitor<br />
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| **[[1f92]], [[1sc8]], [[1vj9]], [[1vja]], [[2o8t]], [[2o8u]], [[2o8w]], [[4h42]], [[4mnv]],[[5wxt]] - hUK (mutant) + inhibitor<br />
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| **[[1fv9]] – hUK (mutant) + benzimidazole derivative <br />
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| **[[5yc6]], [[5yc7]] - hUK (mutant) + benzylamine derivative<br />
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| **[[1f5k]] - hUK (mutant) + benzamidine derivative<br />
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| **[[1f5l]] - hUK (mutant) + amiloride derivative<br />
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| **[[1owd]], [[1owe]], [[1owh]], [[1owi]], [[1owj]], [[1owk]], [[1sqa]], [[1sqo]], [[1u6q]], [[1sqt]], [[4fuc]], [[4fud]], [[4fue]], [[4fuf]], [[4fug]], [[4fuh]], [[4fui]], [[4fuj]]- hUK + naphthamidine inhibitor<br />
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| **[[6nmb]]- hUK + tranexamic acid inhibitor<br />
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| **[[1ejn]] - hUK (mutant) + urea derivative inhibitor<br />
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| **[[2vin]], [[2vio]], [[2vip]], [[2viq]], [[2viv]], [[2viw]] - hUK (mutant) + mexiletine derivative<br />
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| **[[3qn7]], [[4jk5]], [[4jk6]], [[4x1n]], [[4x1q]], [[4x1r]], [[4x1s]], [[4x0w]], [[4x1p]], [[4zhl]], [[4zhm]], [[4zkn]], [[4zko]], [[4zkr]], [[4zks]] - hUK (mutant) + peptide inhibitor<br />
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| **[[4mnw]], [[4mnx]], [[4mny]], [[4os1]], [[4os2]], [[4os4]], [[4os5]], [[4os6]], [[4os7]] - hUK (mutant) + bicyclic peptide <br />
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| **[[2vnt]], [[2r2w]] - hUK + guanidine derivative<br />
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| **[[5xg4]] - hUK + quercetin<br />
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| **[[1w0z]], [[1w10]], [[1w11]], [[1w12]], [[1w13]], [[1w14]] - hUK + alanineamide derivative<br />
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| **[[6xvd]]- hUK + UPAIN-1-W3F<br />
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| **[[5wxf]]- hUK + UPAIN-2<br />
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| **[[5wxo]]- hUK + UPAIN-2-W3F<br />
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| **[[5wxp]]- hUK + UPAIN-2-3-W3F<br />
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| **[[5wxr]]- hUK + UPAIN-2-4-W3F<br />
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| *Urokinase C terminal complex with inhibitors
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| **[[3kgp]] – hUK Hc C terminal (mutant) + benzoic acid derivative<br />
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| **[[3khv]] - hUK Hc C terminal (mutant) + methanol derivative<br />
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| **[[3mwi]] - hUK Hc C terminal (mutant) + amidine derivative<br />
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| **[[3ox7]], [[3oy5]], [[3oy6]] - hUK Hc C terminal (mutant) + peptide inhibitor<br />
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| **[[3kid]], [[3mhw]] - hUK Hc C terminal (mutant) + aminobenzothiazole derivative<br />
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| **[[2nwn]], [[4gly]] - hUK Hc C terminal + cyclic peptide<br />
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| **[[3m61]] - hUK Hc C terminal (mutant) + cyclic peptide
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| *Urokinase short chain + catalytic domain complex with inhibitors
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| **[[1lmw]] – hUK A+B catalytic domain + EGRCMK<br />
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| **[[1c5w]], [[1c5x]], [[1c5y]], [[1c5z]] - hUK A+B chain catalytic domain + carboxamidine derivative<br />
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| **[[1gi7]], [[1gi8]], [[1gi9]], [[1gj7]], [[1gj8]], [[1gj9]], [[1gja]], [[1gjb]], [[1gjc]], [[1gjd]] - hUK A+B chain catalytic domain (mutant) + carboxamidine derivative<br />
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| **[[1o3p]], [[1o5a]], [[1o5b]], [[1o5c]] - hUK A+B chain catalytic domain (mutant) + benzenolate derivative<br />
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| **[[3ig6]] – hUK A+B chain catalytic domain + inhibitor<br />
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| *Urokinase complex with protein
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| **[[2fd6]] – hUK Hc N terminal + antibody + UK receptor<br />
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| **[[3bt1]], [[3bt2]] - hUK Hc N terminal + vitronectin + UK receptor<br />
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| **[[4k24]] - hUK Hc N terminal + vitronectin + antibody<br />
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| **[[3laq]], [[3u73]] - hUK Hc N terminal + UK receptor<br />
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| **[[2i9b]] - hUK Hc N terminal + UK receptor (mutant)<br />
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| **[[3pb1]] - hUK Hc C terminal (mutant) + UK inhibitor<br />
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| **[[4dw2]] - hUK B chain catalytic domain + antibody<br />
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| **[[5hgg]] - hUK catalytic domain (mutant) + antibody<br />
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| **[[5lhn]], [[5lhr]] - mUK catalytic domain (mutant) + antibody<br />
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| **[[5lhp]], [[5lhq]] - mUK catalytic domain (mutant) + antibody + inhibitor<br />
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| }}
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| ==References== | | ==References== |
| <references /> | | <references /> |
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| [[Category:Topic Page]] | | [[Category:Topic Page]] |
