Sandbox Reserved 1625: Difference between revisions

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[[Image:Transmem1.png|300 px|right|thumb|'''Figure 2''. Cartoon model of cytochrome bd-oxidase in ''E. coli''. Dashed lines represent borders of cytoplasmic and extracellular regions.]]

bd Oxidase is a type of quinol-dependent terminal oxidase found exclusively in prokaryotes.<ref name="Safarian">PMID: 27126043</ref> With a very high oxygen affinity, bd oxidases play a vital role in the oxidative phosphorylation pathway in both gram-positive and gram-negative bacteria. bd oxidases responsibility in the oxidative phosphorylation pathway allows the protein to also assist as a key survival factor in the bacterial stress response against antibacterial drugs. <ref name="Safarian">PMID: 31604309</ref> The <scene name='83/832931/Full/4'>cytochrome ''bd'' oxidase</scene> allows bacteria to be resistant to hypoxia, cyanide, nitric oxide, and H2O2<ref name="Harikishore">PMID: 31939065</ref>

bd Oxidase is a type of quinol-dependent terminal oxidase found exclusively in prokaryotes.<ref name="Safarian">PMID: 27126043</ref> With a very high oxygen affinity, bd oxidases play a vital role in the oxidative phosphorylation pathway in both gram-positive and gram-negative bacteria. bd oxidases responsibility in the oxidative phosphorylation pathway allows the protein to also assist as a key survival factor in the bacterial stress response against antibacterial drugs. <ref name="Safarian, Hahn, Mills">PMID: 31604309</ref> The <scene name='83/832931/Full/4'>cytochrome ''bd'' oxidase</scene> allows bacteria to be resistant to hypoxia, cyanide, nitric oxide, and H2O2<ref name="Harikishore">PMID: 31939065</ref>

Given this knowledge, bd oxidases have become an area of scientific research worth pursuing as they could serve as an ideal target for antimicrobial drug development.

Sandbox Reserved 1625: Difference between revisions

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@@ Line 5: / Line 5: @@
 [[Image:Transmem1.png|300 px|right|thumb|'''Figure 2''. Cartoon model of cytochrome bd-oxidase in ''E. coli''. Dashed lines represent borders of cytoplasmic and extracellular regions.]]
-bd Oxidase is a type of quinol-dependent terminal oxidase found exclusively in prokaryotes.<ref name="Safarian">PMID: 27126043</ref>  With a very high oxygen affinity, bd oxidases play a vital role in the oxidative phosphorylation pathway in both gram-positive and gram-negative bacteria. bd oxidases responsibility in the oxidative phosphorylation pathway allows the protein to also assist as a key survival factor in the bacterial stress response against antibacterial drugs. <ref name="Safarian">PMID: 31604309</ref> The <scene name='83/832931/Full/4'>cytochrome ''bd'' oxidase</scene> allows bacteria to be resistant to hypoxia, cyanide, nitric oxide, and H<sub>2</sub>O<sub>2</sub><ref name="Harikishore">PMID: 31939065</ref>
+bd Oxidase is a type of quinol-dependent terminal oxidase found exclusively in prokaryotes.<ref name="Safarian">PMID: 27126043</ref>  With a very high oxygen affinity, bd oxidases play a vital role in the oxidative phosphorylation pathway in both gram-positive and gram-negative bacteria. bd oxidases responsibility in the oxidative phosphorylation pathway allows the protein to also assist as a key survival factor in the bacterial stress response against antibacterial drugs. <ref name="Safarian, Hahn, Mills">PMID: 31604309</ref> The <scene name='83/832931/Full/4'>cytochrome ''bd'' oxidase</scene> allows bacteria to be resistant to hypoxia, cyanide, nitric oxide, and H<sub>2</sub>O<sub>2</sub><ref name="Harikishore">PMID: 31939065</ref>
 Given this knowledge, bd oxidases have become an area of scientific research worth pursuing as they could serve as an ideal target for antimicrobial drug development.