6ygp

TGT WT labelled mit 5F-Trp crystallised at pH 5.5

spinqualitylabelsall models 6ygp, resolution 1.33Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6ygp is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CL, GOL, ZN NonStd Res: FTR Related: 6ygl, 6ygm Activity: tRNA-guanine(34) transglycosylase, with EC number 2.4.2.29 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]

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