Sandbox Reserved 1601: Difference between revisions
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Article Five <ref name="Fan">PMID:29995856</ref> <ref name="Fan"/> | Article Five <ref name="Fan">PMID:29995856</ref> <ref name="Fan"/> | ||
Mitochondrial calcium uniporter (MCU) channels exist in most eukaryotic life, but activity is regulated differently in each clade.<ref name="Baradaran">PMID:29995857</ref> The precise identity of the MCU wasn't discovered until 2011 and was discovered using a combination of NMR spectroscopy, cryo-electron microscopy, and x-ray crystallography.<ref name="Woods">PMID:31869674</ref> | Mitochondrial calcium uniporter (MCU) channels exist in most eukaryotic life, but activity is regulated differently in each clade.<ref name="Baradaran">PMID:29995857</ref> The precise identity of the MCU wasn't discovered until 2011 and was discovered using a combination of NMR spectroscopy, cryo-electron microscopy, and x-ray crystallography.<ref name="Woods">PMID:31869674</ref> Identification of the structure was difficult because it has no apparent sequence similarity to other ion channels.<ref name="Baradaran"/> However, like other ion channels, it is incredibly selective and efficient. The MCU has the ability to only allow Ca^2+ ions | ||
==Structure== | ==Structure== | ||
