Sandbox Reserved 1606: Difference between revisions
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==Disease== | ==Disease== | ||
Dysfunctions in ABCG2 are linked to [https://en.wikipedia.org/wiki/Hyperuricemia hyperuricemia] which can lead to [https://en.wikipedia.org/wiki/Gout gout], [https://en.wikipedia.org/wiki/Kidney_disease kidney disease], and [https://en.wikipedia.org/wiki/Hypertension hypertension], all of which are thought to be the result of impaired transport of uric acid. Additionally, the expression of ABCG2 has been found to correlate with a poor prognosis and treatment outcome of | Dysfunctions in ABCG2 are linked to [https://en.wikipedia.org/wiki/Hyperuricemia hyperuricemia] which can lead to [https://en.wikipedia.org/wiki/Gout gout], [https://en.wikipedia.org/wiki/Kidney_disease kidney disease], and [https://en.wikipedia.org/wiki/Hypertension hypertension], all of which are thought to be the result of impaired transport of uric acid. Additionally, the expression of ABCG2 has been found to correlate with a poor prognosis and treatment outcome of various cancers including breast, ovarian, and lung.<ref name="Jackson"/> | ||
===Cancer=== | ===Cancer=== | ||
