Huntingtin: Difference between revisions

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== Pathology ==
== Pathology ==


The general consensus is that the toxicity originates from the gain of function of mHTT, as the polyQ solely could still stretch and let to the development of neurological symptoms in mice models.
The general consensus is that the toxicity originates from the gain of function of mHTT, as the polyQ solely could still stretch and let to the development of neurological symptoms in mice models <ref>DOI 10.1038/ng0696-196</ref><ref>DOI 10.1016/s0092-8674(00)81369-0</ref><ref>10.1016/s0092-8674(00)80464-x</ref>.
== References ==
== References ==
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