Sandbox Reserved 1613: Difference between revisions
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==General Structure== | ==General Structure== | ||
The ABCG2 protein is comprised of a homodimer which each have two specific domains: one spanning the cell membrane and one involved with nucleotide binding. | The ABCG2 protein is comprised of a homodimer which each have two specific domains: one spanning the cell membrane and one involved with nucleotide binding. | ||
=== | === Mechanism of Substrate Transport === | ||
[[Image:Ligand_Interactions_6ffc.png|400 px|right|thumb|Figure 1: MZ29 bound to cavity 1 of ABCG2 (6ffc). Two MZ29 are shown in sticks and are colored by element. Hydrophobic interactions between the surface of cavity 1 and MZ29 are shown in green.]] | [[Image:Ligand_Interactions_6ffc.png|400 px|right|thumb|Figure 1: MZ29 bound to cavity 1 of ABCG2 (6ffc). Two MZ29 are shown in sticks and are colored by element. Hydrophobic interactions between the surface of cavity 1 and MZ29 are shown in green.]] | ||