Sandbox Reserved 1613: Difference between revisions

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==General Structure==
==General Structure==
The ABCG2 protein is comprised of a homodimer which each have two specific domains: one spanning the cell membrane and one involved with nucleotide binding.  
The ABCG2 protein is comprised of a homodimer which each have two specific domains: one spanning the cell membrane and one involved with nucleotide binding.  
=== Structural highlights ===
=== Mechanism of Substrate Transport ===
[[Image:Ligand_Interactions_6ffc.png|400 px|right|thumb|Figure 1: MZ29 bound to cavity 1 of ABCG2 (6ffc). Two MZ29 are shown in sticks and are colored by element. Hydrophobic interactions between the surface of cavity 1 and MZ29 are shown in green.]]
[[Image:Ligand_Interactions_6ffc.png|400 px|right|thumb|Figure 1: MZ29 bound to cavity 1 of ABCG2 (6ffc). Two MZ29 are shown in sticks and are colored by element. Hydrophobic interactions between the surface of cavity 1 and MZ29 are shown in green.]]