Sandbox Reserved 1600: Difference between revisions

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= Overall Oxygen Reduction Mechanism Summary=

[[Image: CH462 overall mechanism 1.png|300 px|left|thumb|Figure 4. Overall oxidation-reduction mechanism summary.]]

As mentioned above, the purpose of the bd oxidase is to reduce O₂ to 2H₂O using quinol as the reducing substrate, yielding the overall reaction of O₂ + 4H+ + 4e- → 2H₂O. The oxygen comes from the extracellular side of the protein, and enters through the oxygen entry site to <scene name='83/838655/Bd_oxidase_heme_d/2'>Heme D</scene>. This pathway is depicted in orange in Figure 4.

As mentioned above, the purpose of the bd oxidase is to reduce O₂ to 2H₂O using quinol as the reducing substrate, yielding the overall reaction of O₂ + 4H+ + 4e- → 2H₂O. The oxygen comes from the extracellular side of the protein, and enters through the <scene name='83/832926/Potential_oxygen_entry_site/2'>oxygen entry site</scene> to <scene name='83/838655/Bd_oxidase_heme_d/2'>Heme D</scene>. This pathway is depicted in orange in Figure 4.

The electrons required for the reduction mechanism come from a ubiquinol molecule (Fig. 2) that simultaneously binds to the <scene name='83/838655/Bdoxidase_q_loop/3'>Q loop</scene> and gets oxidized giving 4e- to <scene name='83/838655/Bd_oxidase_heme_558/3'>Heme B558</scene>. Once at <scene name='83/838655/Bd_oxidase_heme_558/3'>Heme B558</scene>, the 4e- will be shuttled directly to <scene name='83/838655/Bd_oxidase_heme_d/2'>Heme D</scene> to be used in the reaction. The electron pathway is depicted in blue in Figure 4.

Sandbox Reserved 1600: Difference between revisions

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@@ Line 36: / Line 36: @@
 = Overall Oxygen Reduction Mechanism Summary=
 [[Image: CH462 overall mechanism 1.png|300 px|left|thumb|Figure 4. Overall oxidation-reduction mechanism summary.]]
-As mentioned above, the purpose of the bd oxidase is to reduce O₂ to 2H₂O using quinol as the reducing substrate, yielding the overall reaction of O₂ + 4H<sup>+</sup> + 4e<sup>-</sup> → 2H₂O. The oxygen comes from the extracellular side of the protein, and enters through the oxygen entry site to <scene name='83/838655/Bd_oxidase_heme_d/2'>Heme D</scene>. This pathway is depicted in <font color='orange'><b>orange</b></font> in Figure 4.
+As mentioned above, the purpose of the bd oxidase is to reduce O₂ to 2H₂O using quinol as the reducing substrate, yielding the overall reaction of O₂ + 4H<sup>+</sup> + 4e<sup>-</sup> → 2H₂O. The oxygen comes from the extracellular side of the protein, and enters through the <scene name='83/832926/Potential_oxygen_entry_site/2'>oxygen entry site</scene> to <scene name='83/838655/Bd_oxidase_heme_d/2'>Heme D</scene>. This pathway is depicted in <font color='orange'><b>orange</b></font> in Figure 4.
 The electrons required for the reduction mechanism come from a ubiquinol molecule (Fig. 2) that simultaneously binds to the <scene name='83/838655/Bdoxidase_q_loop/3'>Q loop</scene> and gets oxidized giving 4e<sup>-</sup> to <scene name='83/838655/Bd_oxidase_heme_558/3'>Heme B558</scene>. Once at <scene name='83/838655/Bd_oxidase_heme_558/3'>Heme B558</scene>, the 4e<sup>-</sup> will be shuttled directly to <scene name='83/838655/Bd_oxidase_heme_d/2'>Heme D</scene> to be used in the reaction. The electron pathway is depicted in <font color='blue'><b>blue</b></font> in Figure 4.