User:Samuel Boyson/Sandbox 900: Difference between revisions
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BRD7 along with many other Bromodomains has been widely implicated in a variety of diseases like Cancer. There is increasing evidence that BRD7 is highly downregulated in a variety of human cancers. BRD7 is known to act as a crucial component of both the p53 and BRCA1 oncogenic pathways(2). BRD7 is most notably associated with NPC. In NPC cells, it is frequently found that BRD7 is under expressed, which may play a large role in NPC development and progression(9). When BRD7 is overexpressed, it slows the growth of NPC cells through transcriptional regulation. | BRD7 along with many other Bromodomains has been widely implicated in a variety of diseases like Cancer. There is increasing evidence that BRD7 is highly downregulated in a variety of human cancers. BRD7 is known to act as a crucial component of both the p53 and BRCA1 oncogenic pathways(2). BRD7 is most notably associated with NPC. In NPC cells, it is frequently found that BRD7 is under expressed, which may play a large role in NPC development and progression(9). When BRD7 is overexpressed, it slows the growth of NPC cells through transcriptional regulation. | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
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