Sandbox Reserved 896: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 77: | Line 77: | ||
Sequence Similarity: (39 + 23) / 73 = 85% | Sequence Similarity: (39 + 23) / 73 = 85% | ||
'''As stated above, it is the low level of sequence identity shared between BRD2-BD1 and BRD2-BD2 that allows for selective drug targeting. The sequence identity is most divergent in the regions consisting the ZA and BC loops, with BD2 containing key residues of Leu383 and Asn429.''' | |||
'''Figure 4: BD1 Alignment Among BET Proteins''' | '''Figure 4: BD1 Alignment Among BET Proteins''' | ||