DNA Polymerase Theta: Difference between revisions
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==Structural Description== | ==Structural Description== | ||
<Structure load='4x0p' size='350' frame='true' align='right' caption='DNA polymerase theta polymerase domain in complex with double-stranded DNA substrate and incoming ddATP' ></StructureSection> | |||
Full length polymerase theta consists of an N-terminal helicase-like domain that is connected to the C-terminal polymerase domain by a central linker region. | Full length polymerase theta consists of an N-terminal helicase-like domain that is connected to the C-terminal polymerase domain by a central linker region. | ||
[[Image:Full-lengthpoltheta]] | [[Image:Full-lengthpoltheta.jpg]] | ||
The polymerase domain of polymerase theta (QM1) is a member of the A-family of polymerases which includes Pol I and T7 DNA polymerase. A-family polymerases contain <scene name='84/842971/A-family_motifs/1'>6 conserved motifs</scene> | The polymerase domain of polymerase theta (QM1) is a member of the A-family of polymerases which includes Pol I and T7 DNA polymerase. A-family polymerases contain <scene name='84/842971/A-family_motifs/1'>6 conserved motifs</scene> | ||
== Structural Insights == | == Structural Insights == | ||
== Function == | == Function == | ||
