Sandbox chaperones: Difference between revisions

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== Function ==
== Function ==


The primary function of chaperones is protein folding. They are proteins that assist/chaperone other proteins as they fold or unfold and assemble or disassemble in order to prevent misfolding and unwanted protein aggregation.
The primary function of [[Chaperones]] is protein folding. They are proteins that assist/chaperone other proteins as they fold or unfold and assemble or disassemble in order to prevent misfolding and unwanted protein aggregation.


Some chaperones function closely with ribosomes in order to help fold newly made proteins, sometimes co-translationally. However, most proteins will fold spontaneously without the help of a chaperone. Chaperones become necessary for most proteins only when the intracellular environment becomes too crowded, thus increasing the chances of protein aggregation unless aided by a chaperone.
Some chaperones function closely with ribosomes in order to help fold newly made proteins, sometimes co-translationally. However, most proteins will fold spontaneously without the help of a chaperone. Chaperones become necessary for most proteins only when the intracellular environment becomes too crowded, thus increasing the chances of protein aggregation unless aided by a chaperone.