5fx5: Difference between revisions

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==Novel inhibitors of human rhinovirus 3C protease==
==Novel inhibitors of human rhinovirus 3C protease==
<StructureSection load='5fx5' size='340' side='right' caption='[[5fx5]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5fx5' size='340' side='right'caption='[[5fx5]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fx5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FX5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FX5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fx5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hrv-2 Hrv-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FX5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FX5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HOV:ETHYL+(4R)-4-[[(2S,3R)-1-[(2S)-3-METHYL-2-[(5-METHYL-1,2-OXAZOL-3-YL)CARBONYLAMINO]BUTANOYL]-3-PHENYL-PYRROLIDIN-2-YL]CARBONYLAMINO]-5-[(3S)-2-OXIDANYLIDENEPYRROLIDIN-3-YL]PENTANOATE'>HOV</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HOV:ETHYL+(4R)-4-[[(2S,3R)-1-[(2S)-3-METHYL-2-[(5-METHYL-1,2-OXAZOL-3-YL)CARBONYLAMINO]BUTANOYL]-3-PHENYL-PYRROLIDIN-2-YL]CARBONYLAMINO]-5-[(3S)-2-OXIDANYLIDENEPYRROLIDIN-3-YL]PENTANOATE'>HOV</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fx6|5fx6]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fx6|5fx6]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.22.28 2.4.22.28] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.22.28 2.4.22.28] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fx5 OCA], [http://pdbe.org/5fx5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fx5 RCSB], [http://www.ebi.ac.uk/pdbsum/5fx5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fx5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fx5 OCA], [http://pdbe.org/5fx5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fx5 RCSB], [http://www.ebi.ac.uk/pdbsum/5fx5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fx5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5fx5" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5fx5" style="background-color:#fffaf0;"></div>
==See Also==
*[[Virus proteases 3D strutures|Virus proteases 3D strutures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hrv-2]]
[[Category: Large Structures]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Ek, M]]
[[Category: Ek, M]]
Retrieved from "https://proteopedia.org/5fx5"