5fxs: Difference between revisions
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==IGFR-1R complex with a pyrimidine inhibitor.== | ==IGFR-1R complex with a pyrimidine inhibitor.== | ||
<StructureSection load='5fxs' size='340' side='right' caption='[[5fxs]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5fxs' size='340' side='right'caption='[[5fxs]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5fxs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXS OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5fxs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FXS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=OZN:2-[4-[4-[[(6Z)-5-CHLORANYL-6-PYRAZOLO[1,5-A]PYRIDIN-3-YLIDENE-1H-PYRIMIDIN-2-YL]AMINO]-3,5-DIMETHYL-PYRAZOL-1-YL]PIPERIDIN-1-YL]-N,N-DIMETHYL-ETHANAMIDE'>OZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=OZN:2-[4-[4-[[(6Z)-5-CHLORANYL-6-PYRAZOLO[1,5-A]PYRIDIN-3-YLIDENE-1H-PYRIMIDIN-2-YL]AMINO]-3,5-DIMETHYL-PYRAZOL-1-YL]PIPERIDIN-1-YL]-N,N-DIMETHYL-ETHANAMIDE'>OZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fxq|5fxq]], [[5fxr|5fxr]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fxq|5fxq]], [[5fxr|5fxr]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxs OCA], [http://pdbe.org/5fxs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fxs RCSB], [http://www.ebi.ac.uk/pdbsum/5fxs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fxs ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Boyd, S]] | [[Category: Boyd, S]] | ||