Nerve growth factor: Difference between revisions
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<StructureSection load=' | <StructureSection load='2ifg' size='340' side='right' caption='Caption for this structure' scene=''> | ||
== Function == | == Function == | ||
'''Nerve growth factor''' (NGF) belongs to the family of neurotrophins. NGF promotes survival and differentiation of sensory and sympathetic neurons. NGF signaling furthers neuroprotective and repair functions<ref>PMID:11520933</ref>. | |||
== Relevance == | == Relevance == | ||
Increased cerebrospinal fluid levels of proNGF mark the onset of mild cognitive impairment and the transition to Alzheimer disease suggest that NGF is a potential Alzheimer biomarker<ref>PMID:31312116</ref>. | |||
== Structural highlights == | == Structural highlights == | ||
Revision as of 09:46, 13 May 2020
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3D structures of nerve growth factor
Updated on 13-May-2020
4edk, 4edw, 5jz7 - hβ-NGF + antibody - human
2ifg, 1www - hβ-NGF + TrkA
1sg1 - hβ-NGF + neutrophin receptor
4zbn - hβ-NGF + DNA
6xuo - NGF - horse
1btg, 5lsd, 1sgf, 1bet - mNGF - mouse
4xpj, 4eax - mNGF + lipid
6ffy - mNGF + SorCS2
3ij2 - mNGF + TNFR
4ec7 - NGF + lipid - cobra
