5gsa: Difference between revisions

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==EED in complex with an allosteric PRC2 inhibitor==
==EED in complex with an allosteric PRC2 inhibitor==
<StructureSection load='5gsa' size='340' side='right' caption='[[5gsa]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
<StructureSection load='5gsa' size='340' side='right'caption='[[5gsa]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5gsa]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GSA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GSA FirstGlance]. <br>
<table><tr><td colspan='2'>[[5gsa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GSA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5GSA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=73K:N-(FURAN-2-YLMETHYL)-8-(4-METHYLSULFONYLPHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE'>73K</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=73K:N-(FURAN-2-YLMETHYL)-8-(4-METHYLSULFONYLPHENYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-5-AMINE'>73K</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EED ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gsa OCA], [http://pdbe.org/5gsa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gsa RCSB], [http://www.ebi.ac.uk/pdbsum/5gsa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gsa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5gsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gsa OCA], [http://pdbe.org/5gsa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gsa RCSB], [http://www.ebi.ac.uk/pdbsum/5gsa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gsa ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5gsa" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5gsa" style="background-color:#fffaf0;"></div>
==See Also==
*[[Polycomb|Polycomb]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Luo, X]]
[[Category: Luo, X]]
[[Category: Zhang, H]]
[[Category: Zhang, H]]