5h19: Difference between revisions

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==EED in complex with PRC2 allosteric inhibitor EED162==
==EED in complex with PRC2 allosteric inhibitor EED162==
<StructureSection load='5h19' size='340' side='right' caption='[[5h19]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5h19' size='340' side='right'caption='[[5h19]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5h19]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H19 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5h19]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H19 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5H19 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LQF:5-(FURAN-2-YLMETHYLAMINO)-9-(PHENYLMETHYL)-8,10-DIHYDRO-7H-[1,2,4]TRIAZOLO[3,4-A][2,7]NAPHTHYRIDINE-6-CARBONITRILE'>LQF</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LQF:5-(FURAN-2-YLMETHYLAMINO)-9-(PHENYLMETHYL)-8,10-DIHYDRO-7H-[1,2,4]TRIAZOLO[3,4-A][2,7]NAPHTHYRIDINE-6-CARBONITRILE'>LQF</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5h13|5h13]], [[5h14|5h14]], [[5h15|5h15]], [[5h17|5h17]], [[5h24|5h24]], [[5h25|5h25]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5h13|5h13]], [[5h14|5h14]], [[5h15|5h15]], [[5h17|5h17]], [[5h24|5h24]], [[5h25|5h25]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EED ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h19 OCA], [http://pdbe.org/5h19 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h19 RCSB], [http://www.ebi.ac.uk/pdbsum/5h19 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h19 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5h19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h19 OCA], [http://pdbe.org/5h19 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h19 RCSB], [http://www.ebi.ac.uk/pdbsum/5h19 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h19 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5h19" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5h19" style="background-color:#fffaf0;"></div>
==See Also==
*[[Polycomb|Polycomb]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Luo, X]]
[[Category: Luo, X]]
[[Category: Zhang, H]]
[[Category: Zhang, H]]
Retrieved from "https://proteopedia.org/5h19"