Sandbox Reserved 1095: Difference between revisions

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Angiotensin Receptor Blockers (ARBs) are used to cure diseases linked to AT1R.

The ARB [https://en.wikipedia.org/wiki/Olmesartan olmesartan] is anchored to ATR1 by the residues <scene name='82/829348/Tyr35/6'>Tyr35</scene>, <scene name='82/829348/Trp84/5'>Trp84</scene> and <scene name='82/829348/Arg167/3'>Arg167</scene>.

Those three amino acids seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref name="Zhang2015"/>.

<scene name='82/829348/3_residues_bound_to_ligand/1'>Those three amino acids</scene> seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref name="Zhang2015"/>.

Many ARBs contain a [https://en.wikipedia.org/wiki/Tetrazole tetrazole] group. Studies showed that tetrazole plays an important role in the binding with AT1R.

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@@ Line 40: / Line 40: @@
 Angiotensin Receptor Blockers (ARBs) are used to cure diseases linked to AT1R.
 The ARB [https://en.wikipedia.org/wiki/Olmesartan olmesartan] is anchored to ATR1 by the residues <scene name='82/829348/Tyr35/6'>Tyr35</scene>, <scene name='82/829348/Trp84/5'>Trp84</scene> and <scene name='82/829348/Arg167/3'>Arg167</scene>.
-Those three amino acids seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref name="Zhang2015"/>.
+<scene name='82/829348/3_residues_bound_to_ligand/1'>Those three amino acids</scene> seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref name="Zhang2015"/>.
 Many ARBs contain a [https://en.wikipedia.org/wiki/Tetrazole tetrazole] group. Studies showed that tetrazole plays an important role in the binding with AT1R.