5i3y: Difference between revisions
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==Crystal structure of BACE1 in complex with aminoquinoline inhibitor 9== | ==Crystal structure of BACE1 in complex with aminoquinoline inhibitor 9== | ||
<StructureSection load='5i3y' size='340' side='right' caption='[[5i3y]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='5i3y' size='340' side='right'caption='[[5i3y]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5i3y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I3Y OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5i3y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I3Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5I3Y FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=68K:N-(6-{2-[2-(2-AMINO-3-{3-[(3,3-DIMETHYLBUTYL)AMINO]-3-OXOPROPYL}QUINOLIN-6-YL)PHENYL]ETHYL}PYRIDIN-3-YL)-4-FLUOROBENZAMIDE'>68K</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=68K:N-(6-{2-[2-(2-AMINO-3-{3-[(3,3-DIMETHYLBUTYL)AMINO]-3-OXOPROPYL}QUINOLIN-6-YL)PHENYL]ETHYL}PYRIDIN-3-YL)-4-FLUOROBENZAMIDE'>68K</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i3x|5i3x]], [[5i3w|5i3w]], [[5i3v|5i3v]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i3x|5i3x]], [[5i3w|5i3w]], [[5i3v|5i3v]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5i3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i3y OCA], [http://pdbe.org/5i3y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i3y RCSB], [http://www.ebi.ac.uk/pdbsum/5i3y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i3y ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5i3y" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5i3y" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Beta secretase 3D structures|Beta secretase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Long, A M]] | [[Category: Long, A M]] | ||
