6yv4: Difference between revisions
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==STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH A PYRROLE-3-CARBOXYLIC ACID FRAGMENT | ==STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH A PYRROLE-3-CARBOXYLIC ACID FRAGMENT 686== | ||
<StructureSection load='6yv4' size='340' side='right'caption='[[6yv4]]' scene=''> | <StructureSection load='6yv4' size='340' side='right'caption='[[6yv4]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YV4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6YV4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[6yv4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YV4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6YV4 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6yv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yv4 OCA], [http://pdbe.org/6yv4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6yv4 RCSB], [http://www.ebi.ac.uk/pdbsum/6yv4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6yv4 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PQK:1-cyclopropyl-2,5-dimethyl-pyrrole-3-carboxylic+acid'>PQK</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NOTUM, OK/SW-CL.30 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Wnt_protein]_O-palmitoleoyl-L-serine_hydrolase [Wnt protein] O-palmitoleoyl-L-serine hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.98 3.1.1.98] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6yv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yv4 OCA], [http://pdbe.org/6yv4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6yv4 RCSB], [http://www.ebi.ac.uk/pdbsum/6yv4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6yv4 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/NOTUM_HUMAN NOTUM_HUMAN]] May deacetylate GlcNAc residues on cell surface glycans. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hillier J]] | [[Category: Hillier, J]] | ||
[[Category: Jones | [[Category: Jones, E Y]] | ||
[[Category: Ruza | [[Category: Ruza, R R]] | ||
[[Category: Fragment screen]] | |||
[[Category: Frizzled]] | |||
[[Category: Fzd]] | |||
[[Category: Hydrolase]] | |||
[[Category: Notum]] | |||
[[Category: Wnt]] | |||
[[Category: Wnt signalling]] | |||
