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==Crystal Structure of the Anaplastic Lymphoma Kinase (ALK) in complex with 5d==
==Crystal Structure of the Anaplastic Lymphoma Kinase (ALK) in complex with 5d==
<StructureSection load='5iuh' size='340' side='right' caption='[[5iuh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='5iuh' size='340' side='right'caption='[[5iuh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5iuh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IUH FirstGlance]. <br>
<table><tr><td colspan='2'>[[5iuh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IUH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=34Y:4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[3-METHYL-4-({[5-(PROPAN-2-YL)-1,2-OXAZOL-3-YL]CARBAMOYL}AMINO)PHENYL]-1H-PYRAZOL-5-YL}BENZAMIDE'>34Y</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=34Y:4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[3-METHYL-4-({[5-(PROPAN-2-YL)-1,2-OXAZOL-3-YL]CARBAMOYL}AMINO)PHENYL]-1H-PYRAZOL-5-YL}BENZAMIDE'>34Y</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iug|5iug]], [[5iui|5iui]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iug|5iug]], [[5iui|5iui]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ALK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuh OCA], [http://pdbe.org/5iuh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iuh RCSB], [http://www.ebi.ac.uk/pdbsum/5iuh PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5iuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuh OCA], [http://pdbe.org/5iuh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iuh RCSB], [http://www.ebi.ac.uk/pdbsum/5iuh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuh ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5iuh" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5iuh" style="background-color:#fffaf0;"></div>
==See Also==
*[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Tu, C H]]
[[Category: Tu, C H]]
Retrieved from "https://proteopedia.org/5iuh"