5k5n: Difference between revisions
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==Crystal structure of GSK-3beta complexed with PF-04802367, a highly selective brain-penetrant kinase inhibitor== | ==Crystal structure of GSK-3beta complexed with PF-04802367, a highly selective brain-penetrant kinase inhibitor== | ||
<StructureSection load='5k5n' size='340' side='right' caption='[[5k5n]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='5k5n' size='340' side='right'caption='[[5k5n]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5k5n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K5N OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5k5n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K5N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5K5N FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6QH:5-(3-CHLORANYL-4-METHOXY-PHENYL)-~{N}-[3-(1,2,4-TRIAZOL-1-YL)PROPYL]-1,3-OXAZOLE-4-CARBOXAMIDE'>6QH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6QH:5-(3-CHLORANYL-4-METHOXY-PHENYL)-~{N}-[3-(1,2,4-TRIAZOL-1-YL)PROPYL]-1,3-OXAZOLE-4-CARBOXAMIDE'>6QH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSK3B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5k5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k5n OCA], [http://pdbe.org/5k5n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k5n RCSB], [http://www.ebi.ac.uk/pdbsum/5k5n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k5n ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5k5n" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5k5n" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Glycogen synthase kinase 3 3D structures|Glycogen synthase kinase 3 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Chang, J S]] | [[Category: Chang, J S]] | ||
[[Category: Kurumbail, R G]] | [[Category: Kurumbail, R G]] | ||
