2ycr: Difference between revisions

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==Crystal structure of checkpoint kinase 2 in complex with inhibitor PV976==
==Crystal structure of checkpoint kinase 2 in complex with inhibitor PV976==
<StructureSection load='2ycr' size='340' side='right' caption='[[2ycr]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2ycr' size='340' side='right'caption='[[2ycr]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ycr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YCR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YCR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ycr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YCR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YCR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HCW:1,3-BIS{4-[(1E)-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)ETHANEHYDRAZONOYL]PHENYL}UREA'>HCW</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCW:1,3-BIS{4-[(1E)-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)ETHANEHYDRAZONOYL]PHENYL}UREA'>HCW</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2xbj|2xbj]], [[2cn8|2cn8]], [[2w0j|2w0j]], [[2ycf|2ycf]], [[2wtc|2wtc]], [[2wtj|2wtj]], [[2xm9|2xm9]], [[2w7x|2w7x]], [[2ycq|2ycq]], [[1gxc|1gxc]], [[2cn5|2cn5]], [[2xm8|2xm8]], [[2wtd|2wtd]], [[2ycs|2ycs]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2xbj|2xbj]], [[2cn8|2cn8]], [[2w0j|2w0j]], [[2ycf|2ycf]], [[2wtc|2wtc]], [[2wtj|2wtj]], [[2xm9|2xm9]], [[2w7x|2w7x]], [[2ycq|2ycq]], [[1gxc|1gxc]], [[2cn5|2cn5]], [[2xm8|2xm8]], [[2wtd|2wtd]], [[2ycs|2ycs]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ycr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ycr OCA], [http://pdbe.org/2ycr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ycr RCSB], [http://www.ebi.ac.uk/pdbsum/2ycr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ycr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ycr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ycr OCA], [http://pdbe.org/2ycr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ycr RCSB], [http://www.ebi.ac.uk/pdbsum/2ycr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ycr ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Jobson, A G]]
[[Category: Jobson, A G]]
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