DNA: Difference between revisions

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The two chains in a DNA are joined by hydrogen bonds between specific bases. Adenine forms base pairs with thymine and guanine with cytosine. This specific base pairing between <scene name='User:Adithya_Sagar/Workbench_newDNA/B-dna/14'>Adenine-Thymine</scene> and <scene name='User:Adithya_Sagar/Workbench_newDNA/B-dna/15'>Guanine-Cytosine</scene> is known as the Watson-Crick base pairing. The specificity of hydrogen bonding between bases leads to complementarity in the sequence of nucleotides in the two chains.<ref name='structure'>A Structure for Deoxyribose Nucleic Acid

Watson J.D. and Crick F.H.C.

Nature 171, 737-738 (1953)</ref> Thus in a strand of DNA the content of adenine is equal to that of thymine and the guanine content is equal to the cytosine content. In general DNA with higher GC content is more stable than the one with higher AT content owing to the stabilization due to base stacking interactions.

Nature 171, 737-738 (1953)</ref> Thus in a strand of DNA the content of adenine is equal to that of thymine and the guanine content is equal to the cytosine content. In general DNA with higher GC content is more stable than the one with higher AT content owing to the stabilization due to [[base stacking]] interactions.

=== DNA denaturation and renaturation ===

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 The two chains in a DNA are joined by hydrogen bonds between specific bases. Adenine forms base pairs with thymine and guanine with cytosine. This specific base pairing between <scene name='User:Adithya_Sagar/Workbench_newDNA/B-dna/14'>Adenine-Thymine</scene> and <scene name='User:Adithya_Sagar/Workbench_newDNA/B-dna/15'>Guanine-Cytosine</scene> is known as the Watson-Crick base pairing.  The specificity of hydrogen bonding between bases leads to complementarity in the sequence of nucleotides in the two chains.<ref name='structure'>A Structure for Deoxyribose Nucleic Acid
 Watson J.D. and Crick F.H.C.
-Nature 171, 737-738 (1953)</ref> Thus in a strand of DNA the content of adenine is equal to that of thymine  and the guanine content is equal to the cytosine content.  In general DNA with higher GC content is more stable than the one with higher AT content owing to the stabilization due to base stacking interactions.
+Nature 171, 737-738 (1953)</ref> Thus in a strand of DNA the content of adenine is equal to that of thymine  and the guanine content is equal to the cytosine content.  In general DNA with higher GC content is more stable than the one with higher AT content owing to the stabilization due to [[base stacking]] interactions.
 === DNA denaturation and renaturation ===