6tpk: Difference between revisions
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== | ==Crystal structure of the human oxytocin receptor== | ||
<StructureSection load='6tpk' size='340' side='right'caption='[[6tpk]]' scene=''> | <StructureSection load='6tpk' size='340' side='right'caption='[[6tpk]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TPK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TPK FirstGlance]. <br> | <table><tr><td colspan='2'>[[6tpk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TPK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TPK FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tpk OCA], [http://pdbe.org/6tpk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tpk RCSB], [http://www.ebi.ac.uk/pdbsum/6tpk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tpk ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NU2:(3~{R},6~{R})-6-[(2~{S})-butan-2-yl]-3-(2,3-dihydro-1~{H}-inden-2-yl)-1-[(1~{R})-1-(2-methyl-1,3-oxazol-4-yl)-2-morpholin-4-yl-2-oxidanylidene-ethyl]piperazine-2,5-dione'>NU2</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OXTR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tpk OCA], [http://pdbe.org/6tpk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tpk RCSB], [http://www.ebi.ac.uk/pdbsum/6tpk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tpk ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/OXYR_HUMAN OXYR_HUMAN]] Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ehrenmann J]] | [[Category: Ehrenmann, J]] | ||
[[Category: Kummer L]] | [[Category: Kummer, L]] | ||
[[Category: Plueckthun A]] | [[Category: Plueckthun, A]] | ||
[[Category: Schoeppe J]] | [[Category: Schoeppe, J]] | ||
[[Category: Waltenspuehl Y]] | [[Category: Waltenspuehl, Y]] | ||
[[Category: Eukaryotic]] | |||
[[Category: Hormone receptor]] | |||
[[Category: Protein]] | |||
