Sandbox GGC1: Difference between revisions

Revision as of 23:51, 15 September 2020

Histone H3.2

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-'''6ATF'''
+'''Histone H3.2'''
 <StructureSection load='6ATF' size='340' side='right' caption='Caption for this structure' scene=''>
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 == Function ==
-[https://www.uniprot.org/uniprot/P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha] is a Precursor of the Processed cyclic AMP-dependent transcription factor ATF-6 alpha and it is located in the endoplasmic reticulum membrane.
+https://www.uniprot.org/uniprot/Q71DI3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which [require DNA as a template]. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 == Disease ==