Sandbox GGC1: Difference between revisions
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== Function == | == Function == | ||
The Variant | The Variant[https://www.uniprot.org/uniprot/P84243 histone H3] replaces H3 in a range of nucleosomes in active genes. Deposited at sites of nucleosomal displacement throughout transcribed genes which represents an epigenetic imprint of active chromatin. Nucleosomes wrap and compact DNA into chromatin. Also Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling | ||
== Disease == | == Disease == | ||