5v71: Difference between revisions
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==KRAS G12C in bound to quinazoline based switch II pocket (SWIIP) binder== | ==KRAS G12C in bound to quinazoline based switch II pocket (SWIIP) binder== | ||
<StructureSection load='5v71' size='340' side='right' caption='[[5v71]], [[Resolution|resolution]] 2.23Å' scene=''> | <StructureSection load='5v71' size='340' side='right'caption='[[5v71]], [[Resolution|resolution]] 2.23Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5v71]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V71 OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5v71]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V71 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5V71 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8ZG:1-{4-[6-chloro-7-(2-fluorophenyl)quinazolin-4-yl]piperazin-1-yl}propan-1-one'>8ZG</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8ZG:1-{4-[6-chloro-7-(2-fluorophenyl)quinazolin-4-yl]piperazin-1-yl}propan-1-one'>8ZG</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5v71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v71 OCA], [http://pdbe.org/5v71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v71 RCSB], [http://www.ebi.ac.uk/pdbsum/5v71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v71 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5v71" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5v71" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[GTPase KRas 3D structures|GTPase KRas 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Lu, J]] | [[Category: Lu, J]] | ||
[[Category: Westover, K]] | [[Category: Westover, K]] | ||
