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==Crystal Structure of KDM4 with the Small Molecule Inhibitor QC6352==
==Crystal Structure of KDM4 with the Small Molecule Inhibitor QC6352==
<StructureSection load='5vgi' size='340' side='right' caption='[[5vgi]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
<StructureSection load='5vgi' size='340' side='right'caption='[[5vgi]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5vgi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VGI FirstGlance]. <br>
<table><tr><td colspan='2'>[[5vgi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VGI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5VGI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9DJ:3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic+acid'>9DJ</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9DJ:3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic+acid'>9DJ</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vgk|5vgk]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vgk|5vgk]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vgi OCA], [http://pdbe.org/5vgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vgi RCSB], [http://www.ebi.ac.uk/pdbsum/5vgi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vgi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5vgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vgi OCA], [http://pdbe.org/5vgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vgi RCSB], [http://www.ebi.ac.uk/pdbsum/5vgi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vgi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5vgi" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5vgi" style="background-color:#fffaf0;"></div>
==See Also==
*[[Jumonji domain-containing protein 3D structures|Jumonji domain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Hosfield, D J]]
[[Category: Hosfield, D J]]
[[Category: Demethylase]]
[[Category: Demethylase]]

Revision as of 08:36, 30 September 2020

Crystal Structure of KDM4 with the Small Molecule Inhibitor QC6352

5vgi, resolution 2.07Å

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