5vo6: Difference between revisions

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==CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN IN COMPLEX WITH A PYRROLOPYRIDAZINE INHIBITOR==
==CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN IN COMPLEX WITH A PYRROLOPYRIDAZINE INHIBITOR==
<StructureSection load='5vo6' size='340' side='right' caption='[[5vo6]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='5vo6' size='340' side='right'caption='[[5vo6]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5vo6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VO6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VO6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5vo6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VO6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5VO6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9J4:4-{[(1R,3S)-3-amino-2,2,3-trimethylcyclopentyl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide'>9J4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9J4:4-{[(1R,3S)-3-amino-2,2,3-trimethylcyclopentyl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide'>9J4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vo6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vo6 OCA], [http://pdbe.org/5vo6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vo6 RCSB], [http://www.ebi.ac.uk/pdbsum/5vo6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vo6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5vo6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vo6 OCA], [http://pdbe.org/5vo6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vo6 RCSB], [http://www.ebi.ac.uk/pdbsum/5vo6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vo6 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5vo6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5vo6" style="background-color:#fffaf0;"></div>
==See Also==
*[[Janus kinase 3D structures|Janus kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Sack, J S]]
[[Category: Sack, J S]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transferase-inhibitor complex]]
[[Category: Transferase-inhibitor complex]]