6rng: Difference between revisions
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==Dipeptide Gly-Pro binds to a glycolytic enzyme fructose bisphosphate aldolase== | ==Dipeptide Gly-Pro binds to a glycolytic enzyme fructose bisphosphate aldolase== | ||
<StructureSection load='6rng' size='340' side='right'caption='[[6rng]]' scene=''> | <StructureSection load='6rng' size='340' side='right'caption='[[6rng]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RNG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RNG FirstGlance]. <br> | <table><tr><td colspan='2'>[[6rng]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RNG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RNG FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rng OCA], [http://pdbe.org/6rng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rng RCSB], [http://www.ebi.ac.uk/pdbsum/6rng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rng ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FBA6, At2g36460 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rng OCA], [http://pdbe.org/6rng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rng RCSB], [http://www.ebi.ac.uk/pdbsum/6rng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rng ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/ALFC6_ARATH ALFC6_ARATH]] Fructose-bisphosphate aldolase that plays a key role in glycolysis and gluconeogenesis (PubMed:21782461). Associates with GAPC1 to the outer mitochondrial membrane, in a redox-dependent manner, leading to binding and bundling of actin. Actin binding and bundling occurs under oxidizing conditions and is reversible under reducing conditions. May be part of a redox-dependent retrograde signal transduction network for adaptation upon oxidative stress (PubMed:23316205).<ref>PMID:21782461</ref> <ref>PMID:23316205</ref> | |||
==See Also== | |||
*[[Aldolase 3D structures|Aldolase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Arath]] | |||
[[Category: Fructose-bisphosphate aldolase]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Shahar A]] | [[Category: Shahar, A]] | ||
[[Category: Skirycz A]] | [[Category: Skirycz, A]] | ||
[[Category: Wojciechowska I]] | [[Category: Wojciechowska, I]] | ||
[[Category: Zarivach R]] | [[Category: Zarivach, R]] | ||
[[Category: Peptide binding protein]] | |||
