4ux4: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:


==Crystal structure of human tankyrase 2 in complex with 1-methyl-7-(4- methylphenyl)-5-oxo-5,6-dihydro-1,6-naphthyridin-1-ium==
==Crystal structure of human tankyrase 2 in complex with 1-methyl-7-(4- methylphenyl)-5-oxo-5,6-dihydro-1,6-naphthyridin-1-ium==
<StructureSection load='4ux4' size='340' side='right' caption='[[4ux4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4ux4' size='340' side='right'caption='[[4ux4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ux4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UX4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ux4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UX4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4UX4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E9L:(1S)-1-METHYL-7-(4-METHYLPHENYL)-5-OXO-1,5-DIHYDRO-1,6-NAPHTHYRIDIN-1-IUM'>E9L</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E9L:(1S)-1-METHYL-7-(4-METHYLPHENYL)-5-OXO-1,5-DIHYDRO-1,6-NAPHTHYRIDIN-1-IUM'>E9L</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ux4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ux4 OCA], [http://pdbe.org/4ux4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ux4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ux4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ux4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4ux4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ux4 OCA], [http://pdbe.org/4ux4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ux4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ux4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ux4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
Line 21: Line 21:


==See Also==
==See Also==
*[[Poly (ADP-ribose) polymerase|Poly (ADP-ribose) polymerase]]
*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 27: Line 27:
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Haikarainen, T]]
[[Category: Haikarainen, T]]
[[Category: Lehtio, L]]
[[Category: Lehtio, L]]