Sandbox GGC2: Difference between revisions
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Actin is a family of globular proteins that form microfilaments. It is the most abundant protein in eukaryotes <ref>DOI: 10.1073/pnas.122126299</ref>. They can be found in virtually all eukaryotic cells and come in two main forms, F-actin and G actin. Actin is responsible for many contraction properties in muscles. | Actin is a family of globular proteins that form microfilaments. It is the most abundant protein in eukaryotes <ref>DOI: 10.1073/pnas.122126299</ref>. They can be found in virtually all eukaryotic cells and come in two main forms, F-actin and G actin. Actin is responsible for many contraction properties in muscles. | ||
Vertebrates have 3 main groups of actin isoforms, alpha, beta, and gamma. Alpha actins play a major role in muscle contraction mechanism. Beta and gamma actins are involved in the regulation of cell motility. Actin has the capability to bind with other molecules, most notably myosin and ATP, in order to carry out its function. | Vertebrates have 3 main groups of actin isoforms, alpha, beta, and gamma. Alpha actins play a major role in muscle contraction mechanism. Beta and gamma actins are involved in the regulation of cell motility. Actin has the capability to bind with other molecules, most notably myosin and ATP, in order to carry out its function. | ||
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