Sandbox GGC6: Difference between revisions
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This is the <scene name='78/781192/3ghg/3'>structure of fibrinogen</scene>. It is composed of one pairs of alpha, beta, and gamma polypeptides. the polypeptides are oriented to <scene name='78/781192/N-c_terms/3'>N-terms</scene>ends meet to form a central E domain which is showed in blue. Both domain on the side of E domain called D domain. The N terms ends of polypeptides are cleaved by thrombin to form gel forming fibrin from soluble fibrin <ref>PMID: 28101869 </ref>. | This is the <scene name='78/781192/3ghg/3'>structure of fibrinogen</scene>. It is composed of one pairs of alpha, beta, and gamma polypeptides. the polypeptides are oriented to <scene name='78/781192/N-c_terms/3'>N-terms</scene>ends meet to form a central E domain which is showed in blue. Both domain on the side of E domain called D domain. The N terms ends of polypeptides are cleaved by thrombin to form gel forming fibrin from soluble fibrin <ref>PMID: 28101869 </ref>. | ||
The | The black line is <scene name='78/781192/Asp_364/1'>Asp 364</scene>, which is an important residue. The mutation of this residue can cause Congenital Dysfibrinogenemia. <ref>doi.org/10.1054</ref> | ||
This is a <scene name='78/781192/Hydrophobic_and_polar/3'>hydrophilic and hydrophobic</scene> structure. <ref>doi.org/10.1007/BF01024625(/ref> | This is a <scene name='78/781192/Hydrophobic_and_polar/3'>hydrophilic and hydrophobic</scene> structure. <ref>doi.org/10.1007/BF01024625(/ref> | ||
