1u90: Difference between revisions

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==Crystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap==
==Crystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap==
<StructureSection load='1u90' size='340' side='right' caption='[[1u90]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1u90' size='340' side='right'caption='[[1u90]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1u90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cotton-top_tamarin Cotton-top tamarin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U90 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1u90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cotton-top_tamarin Cotton-top tamarin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U90 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1U90 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u8y|1u8y]], [[1u8z|1u8z]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u8y|1u8y]], [[1u8z|1u8z]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rala, Ral-a, Ral ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9490 Cotton-top tamarin])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rala, Ral-a, Ral ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9490 Cotton-top tamarin])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u90 OCA], [http://pdbe.org/1u90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u90 RCSB], [http://www.ebi.ac.uk/pdbsum/1u90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1u90 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1u90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u90 OCA], [http://pdbe.org/1u90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u90 RCSB], [http://www.ebi.ac.uk/pdbsum/1u90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1u90 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u9/1u90_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u9/1u90_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</StructureSection>
</StructureSection>
[[Category: Cotton-top tamarin]]
[[Category: Cotton-top tamarin]]
[[Category: Large Structures]]
[[Category: Kosak, J]]
[[Category: Kosak, J]]
[[Category: Mattos, C]]
[[Category: Mattos, C]]
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[[Category: Gtp]]
[[Category: Gtp]]
[[Category: Gtpase]]
[[Category: Gtpase]]
[[Category: Ra]]
[[Category: Ral]]
[[Category: Ral]]
[[Category: Ra]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]